Projects

(Project-Number and Title / Research Area / Principal Investigator/s)

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P1 Structure and function of archaeal transporters

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Biophysics, electron microscopy, protein crystallography
Prof. Dr. Werner Kühlbrandt, Department of Structural Biology, Max-Planck-Institute of Biophysics, Frankfurt a.M.
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P2 Synergies of cell-free expression systems and NMR spectroscopy for the analysis of membrane proteins

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Liquid state NMR, biochemistry of membrane proteins
Prof. Dr. Volker Dötsch / Dr. Frank Bernhard, Institute of Biophysical
Chemistry, Goethe-University Frankfurt a.M.

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P3 Structural genomics on selected families of secondary active transporters

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Biochemistry, structural biology
Prof. Dr. Hartmut Michel, Molecular Membrane Biology,
Max-Planck-Institute of Biophysics, Frankfurt a.M

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P4 Structure and function of the betaine transporter BetP from Corynebacterium glutamicum

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Biophysics, structural biology, protein crystallography
Dr. Christine Ziegler, Department of Structural Biology,
Max-Planck-Institute of Biophysics, Frankfurt a.M.
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P5 Structural properties, activation mechanisms and transport processes in betaine transporter BetP and Na⁺/H⁺ antiporters NhaA/MjNhaP1 investigated by FT-IR and CD spectroscopy

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Biophysics, biophysical chemistry, molecular spectroscopy
Prof. Dr. Werner Mäntele, Institute of Biophysics,
Goethe-University Frankfurt a.M.
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P6 Structure and function of bacterial multidrug efflux pumps

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Membrane biophysics, membrane biochemistry, soldi-state NMR, active transport, multidrug efflux
Prof. Dr. Clemens Glaubitz, Institute of Biophysical Chemistry,
Goethe-University Frankfurt a.M.
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P7 Dipolar EPR spectroscopy on membrane embedded transport complexes

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Biophysics, EPR spectroscopy
Prof. Dr. Thomas Prisner, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt a.M.
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P8 Computational studies of alternating access mechanisms in sodium-dependent secondary transporters

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Molecular modeling, bioinformatics and simulation
Dr. Lucy Forrest, Computational Structural Biology Group,

Max-Planck-Institute of Biophysics, Frankfurt a.M.
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P9 Function, mechanism and dynamics of the lysosomal transport complex ABCB9

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Membrane biochemistry, structural biology, cell biology

PD Dr. Rupert Abele, Institute of Biochemistry,
Goethe-University Frankfurt a.M.

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P10 Light gated ion channels and secondary active transporters: mechanism and application

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Biophysics, transport mechanism, electrophysiology, spectroscopy
Prof. Dr. Klaus Fendler / Prof. Dr. Ernst Bamberg,
Max-Planck-Institute of Biophysics, Frankfurt a.M.
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P11 Channelrhodopsin-2 and Halorhodopsin - optogentic tools for fast, non-invasive manipulation of neuronal circuits

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Photo-activated ion-channels & -pumps, membrane protein engineering, neurobiology, neurotransmission, cell biology

Prof. Dr. Alexander Gottschalk, Frankfurt Institute for Molecular Life Sciences (FMLS) & Institute of Biochemistry, Goethe-University Frankfurt
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P12 Photoinitiated functional dynamics of retinal proteins and multidrug transporters

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Biophysics, physical chemistry, molecular spectroscopy
Prof. Dr. Josef Wachtveitl, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt a.M.

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