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Projects

(Project-Number and Title / Research Area / Principal Investigator/s)

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P1  Structure and mechanisms of membrane transport proteins

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Electron Microscopy, protein crystallography, biophysics 

Prof. Dr. Werner Kühlbrandt, Department of Structural Biology,
Max Planck Institute of Biophysics, Frankfurt a.M.
> more

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P2  Cell-free expression of GPCRs: In vitro characterization of the endothelin receptor signal perception and transduction

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Biochemistry, structural biology
Prof. Dr. Volker Dötsch
/ Dr. Frank Bernhard, Institute of Biophysical
Chemistry, Goethe-University Frankfurt a.M.

                           > more

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P3  Structural genomics on selected families of secondary active transporters

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Biochemistry, X-ray crystallography, membrane protein production
Prof. Dr. Hartmut Michel
, Molecular Membrane Biology,
Max Planck Institute of Biophysics, Frankfurt a.M

                           > more

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P4  Dynamic molecular description of transport regulation in BetP

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Structural biology, biophysics, membrane protein biochemistry
Prof. Dr. Christine Ziegler, Department of Structural Biology,
Max Planck Institute of Biophysics, Frankfurt a.M. and Institute of Biophysics & Biophysical Chemistry, Regensburg University
                          > more

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P6  Biophysics of light-driven ion and ABC efflux pumps

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Membrane proteins, biophysics, solid-state NMR
Prof. Dr. Clemens Glaubitz
, Institute of Biophysical Chemistry,
Goethe-University Frankfurt a.M.
>more

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P7  Dipolar EPR spectroscopy on membrane embedded transport complexes

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Biophysics, EPR spectroscopy
Prof. Dr. Thomas Prisner
, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt a.M.
>more

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P9  Function and mechanism of the lysosomal polypeptide transporter ABCB9

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Membrane biochemistry, structural biology, cell biology

PD Dr. Rupert Abele, Institute of Biochemistry,
Goethe-University Frankfurt a.M.

>more

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P10  Light gated ion channels and secondary active transporters:
mechanism and application

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Biophysics, transport mechanism, electrophysiology, spectroscopy
Prof. Dr. Klaus Fendler / Prof. Dr. Ernst Bamberg
,
Max Planck Institute of Biophysics, Frankfurt a.M.
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P11  Microbial rhodopsins as optogenetic tools to analyze neuronal networks in the nematode Caenorhabditis elegans

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Molecular/cellular neuroscience, optogentics, neurophysiology

Prof. Dr. Alexander Gottschalk, Buchmann Institute for Molecular Life Sciences & Institute of Biochemistry, Goethe-University Frankfurt a.M.
>more

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P12  Photoinitiated functional dynamics of retinal proteins

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Biophysics, physical chemistry, molecular spectroscopy
Prof. Dr. Josef Wachtveitl, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt a.M.

> more

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P13  NMR investigations of retinal binding proteins

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      NMR-spectroscopy, structural biology, organic chemistry

      Prof. Dr. Harald Schwalbe, Institute of Organic Chemistry & 

      Chemical Biology, Goethe-University Frankfurt a.M.

      > more

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P14   Structure and function of unusual ATP synthases

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     Microbiology, biochemistry
     Prof. Dr. Volker Müller, Institute of Molecular Biosciences, 

     Goethe-University Frankfurt a.M.

     > more

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P15  Structure and function of bacterial ATP synthases

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Biochemistry, structural biology

Dr. Thomas Meier, Department of Structural Biology,
Max Planck Institute of Biophysics, Frankfurt a.M.

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P16  Translocation mechanism and viral inhibition of the MHC I peptide-loading complex

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Membrane biochemistry, membrane biophysics, ABC transporter

Prof. Dr. Robert Tampé, Institute of Biochemistry,
Goethe-University Frankfurt a.M.

> more

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P17  Structure, function and dynamics of the Toc core complex

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Plant cell / membrane protein biology, biochemistry / biophysics

Prof. Dr. Enrico Schleiff, Institute of Molecular Biosciences,
Goethe-University Frankfurt a.M.

> more

 

P18  Structure and function of Resistance Nodulation and cell Devision (RND) transporters and RND-type tripartite complexes 

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Membrane biochemistry, structural biology, multidrug efflux

Prof. Dr. Klaas Martinus Pos, Institute of Biochemistry,
Goethe-University Frankfurt a.M.

                           > more

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P19  Structural organization of macromolecular complexes in membranes: 
The MHC class I peptide-loading complex

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Computational biology, structural biology
Dr. Lars Schäfer, Institute of Physical and Theoretical Chemistry, Goethe-University Frankfurt a.M.
> more

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P21  Communication of membrane stress by lipids and proteins

 

     Membrane biochemistry, cell biology
     Jun. Prof. Dr. Robert Ernst, Buchmann Institute for Molecular Life
     Sciences & Institute of Biochemistry,
     Goethe-University Frankfurt a.M.
     > more

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